"Spider-man: No Way Home" swung from record to record over the weekend, earning $260 million from U.S. theaters to become the second biggest ever debut in the history of Hollywood.

Meanwhile, across the globe, the film pulled in $340.8 million, bringing its total ticket sales to $600.8 million over the course of just a few short days.

Ultimately the film is the biggest release of this year and the last and is well on its way to being the first to gross $1 billion since the start of the pandemic.

Given the emergence of the viciously contagious Omicron variant, analysts had struggled to ballpark how well the epic finale to the Tom Holland-led trilogy would fare over the weekend. But the film's strong showing proves just how far audiences are willing to go for their fix of superhero-led spectacle.

No doubt "No Way's" performance will be a boon for struggling theater owners. AMC (AMC  ) , the world's largest theater, chain reported that it sold 7 million tickets over the weekend, the first time it has seen 1 million daily ticket sales since 2019's "Star Wars: The Rise of SkyWalker."

"Historically, December is one of the biggest months of the year for major blockbuster releases, so to see 'Spider-Man: No Way Home' set a new all-time opening weekend box office record this month is significant not just for AMC, but for the entire theatrical industry," said CEO Adam Aron.

At the time of writing, shares of AMC are up 19%, with analysts expecting this quarter to be the chain's strongest showing since the onset of the pandemic.

Meanwhile, "No Way," holds a hugely impressive 94% rating on Rotten Tomatoes based on 324 critical reviews.

It's possible that the buzz surrounding"No Way" could crowd out other major releases due this week, including "The Matrix Resurrections" and "Sing 2."

After all, in a single weekend, Spider-man has handily beat the entire slate of superhero movies released this year, including the latest entries in the much-beloved Marvel Comic Universe.

For instance, Black Widow has earned $379 million globally thus far, "Shang-Chi: The Legend of the Ten Rings," 432, and "the Eternals" $39, all falling well short of Spidey's $600.8.

However, Sony (SNE  ) has managed to place the Tom Holland version of the character both in the MCU and in its own Spider-man-centric universe, anchored by our beloved hero and villains Morbius, Craven, and Venom.

"Venom: Let There Be Carnage," the first entry in this new universe, pulled in an impressive $498 million globally and ranks as the third-biggest US release this year.

Meanwhile, Morbius is set to come to big screens on January 20, 2022, while Craven is set to get his debut on January, 13 2023. Results from those films will likely prove a test of "No Way's" staying power.

"The splash effect for other Sony-Marvel adaptations could be significant, but time will tell. Each movie is its own entity from production to marketing to release and reception," Shawn Robbins Chief analyst at Box Office Pro told Variety. "As easy as Marvel Studios makes it look sometimes, there is no one-size-fits-all approach."